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English physicist who worked on radar and magnetic mine development during World War II. After the war, with
James Watson he pondered Wilkins and Rosalind Franklin's
X-ray diffraction data and tried to construct a physical model of DNA. Watson and Crick
believed the model had to be helical based on X-ray diffraction data, and were afraid they were about to be
scooped by Pauling who was hard at work on his alpha helix model. James Watson and Crick
got a much needed clue upon reading Chargaff's paper on one-to-one adenine to thymine and cytosine
to guanine rations. In 1953, after a brainstorm by James Watson, in which he realized that the
shape of the base pairs meant they could only be arranging in a certain way, they published a paper proposing at the
DNA molecule had double helical structure. Crick, James Watson, and Wilkins
shared the 1962 Nobel Prize in medicine and physiology for this discovery, which was subsequently verified
experimentally.
Avery, Chargaff, Franklin (Rosalind), Kornberg, Pauling, Watson (James), Wilkins

Crick, F. The Astonishing Hypothesis: The Scientific Search for the Soul. Touchstone Books, 1995.
Crick, F. Life Itself: Its Origin and Nature. New York: Simon and Schuster, 1981.
Crick, F. Of Molecules and Men. Seattle, WA: University of Washington Press, 1966.
Crick, F. What Mad Pursuit: A Personal View of Scientific Discovery. New York: Basic Books, 1988.
Olby, R. The Path to the Double Helix. Tucson, AZ: University of Arizona Press, 1974.
Watson, J. The Double Helix: A Personal Account of the Discovery of the Structure of DNA. New York: Atheneum, 1980.
© 1996-2007 Eric W. Weisstein
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